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The concomitant usage of opioids with other opioid analgesics, for instance butorphanol, nalbuphine, pentazocine, may well lessen the analgesic effect of acetaminophen and codeine phosphate tablets and/or precipitate withdrawal signs and symptoms.If concomitant use of a CYP3A4 inhibitor is essential or if a CYP3A4 inducer is discontinued, take into